Al-Kunooze Scientific Journal

The N-(4,6-dimethylpyrimidin-2-yl)-4-((11R,15S)-12,14-dioxo-9,10-dihydro-9,10- [3,4] epipyrro-loanthracen-13-yl) benzene sulfonamide was synthesized, characterize, docking and experimentally evaluated as a breast cancer inhibitor. The prepared compound was identified by FT-IR, CHN, 1HNMR, 13CNMR and mass spectrometry. Investigated interactions with human epidermal growth factor receptor 2 HER2( PDB ID: 3PP0) by using virtual screening based on molecular docking to find potential compounds against HER2. The density function theory (DFT) calculation at the B3LYP method with 6‐311+G(d,p) basis set are used to investigate the electronic structure and optimized geometrical structure of the mentioned compounds. Molecular docking against (HER2) (PDB ID:3PP0) showed that compound bind to the HER2. Binding involves two hydrogen bonds were formed between the studied candidate and the amino acids in important residues of the HER2 (PDB ID:3PP0) receptors, the hydrophobic interactions with 9 amino acid also were founds. The effect of the test titled compound on live breast cancer cells, and prepared compound was able to kill 66.932% of breast cancer cells, it was very high percentage. The results have shown that the prepared compound is very effective as an anti-breast cancer candidate.

India is primarily an agrarian nation. Agriculture in India is the core sector for food security, nutritional security, and sustainable development & for poverty alleviation. It contributes approximately 16% of GDP. Farmers in India are struggling to produce under poor environmental conditions with few tools for coping with drought, salinity, pests, and shortages of inputs and lack of appropriate technologies. In view of this problem a survey is performed on applications convolutional neural network in agriculture domain and how convolutional neural network (CNN) technology can boost the efficiency of daily operations in a traditional agriculture and maximize production volume and minimize the possibility of failure due to natural disasters, system errors, and other factors in India. Convolutional neural network is a subset of AI, a modern technique for image processing, with a great potential. Convolutional neural network techniques are successfully applied in various areas such as medical, defence, transport etc. It has recently also entered the domain of agriculture. In this study a survey was conducted on research efforts that employ convolutional neural networks (CNN), which constitute a specific class of deep learning, applied to various agricultural and food production challenges. In this study Convolutional neural networks are compared with other existing techniques, and the advantages and disadvantages of using CNN in agriculture are listed. The overall survey indicates that CNN constitutes a promising technique with high performance in terms of predication and classification accuracy. However, the success of each CNN model is highly dependent on the quality of the data set used.

The Internet of Things (IoT) consists of various devices that interconnection and can be integrated into each component, allowing them to make connections and processing data through internet without human intervention. IoT security is analyzed by papers number of researchers to address their strengths and weakness. This paper summarizes the IoT applications security their defects and advantages in the technology to meet security solutions. This study presented the most prominent research in this field for the last six years, which can be help to secure data within other electronic environments such as E-learning.

In this research paper, surface admission doses for patients resulting from conventional radiography were measured in most known tests (chest, head, abdomen, extremities) for selected devices at the Specialist Surgery Hospital and a private clinic in Baghdad and devices from Different origins have a different manufacturing history, and a group of patients (5 patients) was taken for each examination and according to the resulting dose rate.Surface access dose (ESDpp) was measured using (RMI 240) and surface entry without patient (ESDpa) using two ionization chambers, one of which was German-made attached to a ghost of substance equivalent to living tissue, and the other device was a Swedish-made ionization chamber (Dosimax) (Unfors ). It has been found that thermal flash readings (RMI 240) are more than the rate of ionization readings used, and the difference in dose comes as a result of the dispersion of radiation in the patient's body. The dispersion factor was calculated for all the tests, and it was found that the factor ranges between (1 - 1.2), which is very close to the calculated global values, which amounted to (1.09). The patients ’dose in this research was compared with the approved international values, and it was found that the radiation dose is greater than the reference dose with a range ranging from (1.1 - 1.5) in most devices, and that the range is close to one whenever the device is new, and the radiographer’s experience is good, Because of the importance of quality assurance for X-ray devices (Quality Assurance), time stability was measured for only three of the devices. The mathematical relationship between time and radiation dose is drawn from which the linear coefficient of time is calculated, as it does not exceed 10% for the two devices (A and B), while the linear coefficient is 45% for the apparatus (C).

E-learning in all its forms is a modern educational system that keeps pace with the tremendous technical development witnessed by the world and helps in providing education for all in every place and time and contributes to overcoming a set of obstacles facing traditional education. Countries in providing it and making the e-learning experience successful, while the last section of countries, most of them (developing countries) are still struggling to provide them. Through the research, the researcher aims to clarify the concept of e-learning and identify its basic components.

Polycystic ovary syndrome (PCOS) is one of the most common causes of infertility that cause a massive health and economic costs around the world, it is identified as hyperandrogenism, chronic anovulation and metabolic disorder also chronic inflammation maybe one of the pathogenesis mechanisms in PCOS. due to the increased infertility rates and miscarriage cases in PCOS women and because of the great number of women infected by PCOS in Iraq and in city Basrah in particular, the current study has been designed to evaluate the correlation between proinflammatory cytokines with different biochemical and hormonal parameters in PCOS patients . This study was done in basrah city since 2018, serum samples were collected from 150 women (75 PCOS patients and 75 healthy women) ), blood samples were collected from private gynecological clinic and Basra hospital for Maternity and Children ,relatives and friends, and the required data were collected by using the questionnaire. Then the concentrations of the study parameters were measured by using ELIZA and spectrophotometer methods, the procedure of kits followed accurately as demonstrated in the leaflet with the kit. The results showed a significant positive correlation were obtained between serum IL-18 with cortisol, and a significant positive correlation between serum IL-18 with insulin and TNF-α showed a significantly negative correlation with T4. In conclusion proinflammatory cytokines abnormalities may correlate with the levels of metabolic hormone parameters in PCOS patients.

The problem of the study and its importance Social skills are a key factor in achieving success in dealing with others, especially for those who work in the field of teaching, and there are many means that work to develop social skills, and in our modern age, technology and the Internet have worked to find new ways to develop social skills, which are widely available in educational institutions. It is represented in communication networks, the Internet, and Internet applications by teaching different subjects to the students.

The study dealt with one of the most prominent topics that have recently emerged, which was of pure interest to many economists, and the study included the impact of the Corona virus on the internal and external business environment of business organizations in Iraq. The research problem was to delve into the impact of the Corona pandemic on the stability of the internal business environment of small and medium-sized organizations, as well as its repercussions on the external environment that negatively affected the work of small and medium-sized organizations. These organizations are distributed among the provinces of Najaf and Basra, with six projects in the province of Najaf, and twelve projects in the province of Basra.

Poly pyrrole, poly methyl methacrylate, their composite were prepared and identified by FTIR and UV spectroscopy. The thermal stability of the compounds were studied by TG/DSC thermal analysis. The study shows that the compounds were stable till 225-2500C. The x-ray diffraction shows a kind of crystal structures and the d-spacing of the crystallites were calculated. The dc electrical conductivity of the doped and un-doped polymers were measured and compared.

The aim of the current research is to know the effect of the model of Henish and Molinda (ASSURE) in the achievement of first-grade students in the subject of history. The experimental group that studies history according to the Assyrian model, and Division (B) to represent the control group that studies the same subject according to the traditional method. The number of students in the two groups was (54) students, with (27) students in the experimental group and (27) students in the control group. The two groups were rewarded, and the researcher prepared an achievement test that consisted of (40) multiple-choice test items, whose validity was verified by presenting it to a group of specialists in the methods of teaching history, measurement and evaluation, and its stability through the Kewder-Richard equation. (t-test) to process the data according to the model of Henish and Mulinda (ASSURE) in achievement, and the researcher recommended the necessity of using the ASSURE model in teaching.

The TORCH syndrome is only one health issue. According to health experts, however, TORCH syndrome is a set of various infectious diseases. They can cause serious problems and can damage a fetus' health. Aim of study: To detection the causative agent of abortion in Babylon city –Iraq by using TORCH test.

Talking about the e-educational process remained limited, as long as its scope and application were limited, and in most cases it was limited to virtual university education. However, the emergence of the Corona virus pandemic, and forcing it to apply e-learning, presented this form of learning, its methods and methods to the discussion interface in terms of its positive and negative aspects. and the success of its application. This pandemic has established the idea of ​​comparing distance learning as a complete alternative to classical education, and that distance learning is a complement to classical education. And due to the low quality of service and poor internet infrastructure in IraqIt quickly cast a severe shadow over the educational process. The first is represented by the capacity of the few packages that do not meet the demand in terms of downloading or uploading files for assignments. In addition to the widespread use of free educational platforms and the exceptional momentum gained from the participation of large numbers of students and professors on the same platform, which It affects the platform’s response speed, and in turn affects the timing of lectures and exams and the loss of time waiting for lectures or exam questions to be downloaded. It is also expected that these platforms will not be free in the near future. Due to the limited solutions, the student resorts to spending additional amounts to provide a serviceIt is good through which he can complete his academic career and pass the remaining stages for him, which burdens the student and forces the teacher to do the same in light of the difficult circumstances that our country is going through, especially during this pandemic that we are living in

Belding e-learning is to define the principles of cognitive science for effective learning by integrating traditional simultaneous multiple means using electronic educational technology to enhance learning as it applies many other principles. This learning provides the student with more flexible ways to learn through communication through means provided by modern technology and be The student is the central factor in the learning process with the guidance of the professor. The past years have shown that there is progress in e-learning in Iraq and in the academic year 2019-2020, which is the period of the outbreak of the new Corona virus. There has become an urgent need to use university e-learning platforms such as Google ClassroomBy subject teachers or by universities, these platforms actually played the educational role for which they were created. This paper examines the effectiveness of e-learning for physics in the Department of Physics, College of Education for Pure Sciences at the University of Basra, and the rules of E-Learning in the educational environment in Iraqi universities, specifically in the province of Basra. The application of e-learning alone in universities unless it is mixed with other traditional methods of learning, as well as the difficulty of accepting some teachers at the university to change and go to e-learning because they are not good users of the calculator.

This work propose Free Space Optics Systems (FSO) which is considered as one of the most effective solutions to the optical communication environment. It is intended to design a new modified WDM transmitter operating for 16 channel multi users with Erbium Doped Fiber Amplifier (EDFA). As slicing in Wavelength Division Multiplexer(WDM) systems, in the transmitter channel at frequency 1558nm and chip spacing 0.8 nm , power equal to -23.5dBm,while the output power will record 28.4mw (14.54dBm) measured by the optical power meter. plus by using NRZ modulation format, while the input power is generated with a CW laser, The spectrum-sliced WDM channel operating at high data rate such as 1Gbps,have been transmitted signal to more than 300 Km, no interference occur. This is done by the use of simulation software version 7.

E-learning in all its forms is a modern educational system that keeps pace with the tremendous technical development witnessed by the world and helps in providing education for all in every place and time and contributes to overcoming a set of obstacles facing traditional education. Countries in providing it and making the e-learning experience successful, while the last section of countries, most of them (developing countries) are still struggling to provide them.Through the research, the researcher aims to clarify the concept of e-learning and identify its basic components, and the researcher adhered to the descriptive approach in explaining the concept of e-learning and identifying its components, adopting the analytical method in explaining the advantages of the Iraqi e-learning experience for the academic year 2019 / 2020 AD, and the researcher concluded that e-learning is education Which depends on the use of technology and technological means in education and harnessing them to serve the learner and society as a whole, and that the Iraqi e-educational experience in light of the Corona pandemic is a successful experiment that has won international, regional and national praise.

One of the goals of e-learning in the curricula is to develop the skill of learners and teachers in using twenty-first century technologies through daily learning activities, as e-learning has played a very important role in the current educational scenario and has the potential to change the entire education system as a result of which e-learning has become one of the most Favorite topics of researchers, as research is conducted on e-learning in various disciplines such as communication, education and information technology (IT)And distance education, and researchers work on various aspects of e-learning and for all disciplines. In this study, we analyzed various research works on e-learning to find out research trends in this field, and we conducted an experiment on blended e-learning.In the subject of physics on fourth-grade secondary students in a private secondary school, the virtual lab was used off-line by teachers for all classes of the curriculum. We also conducted an experiment with the PBL problem (Problem Base Learning) and created groups on students of the same school in the second grade The result of the experiment was very encouraging, as the results showed a significant increase in the success rates compared to traditional education, as well as the completion of the prescribed curriculum in record time, as the success rate in the monthly and mid-year exams increased to 95%, while in traditional education for the same time period from the previous year it was 73% for the same Professors and curriculum completion rate were very advanced, and the study showed weakness in the use of twenty-first century technology.