Abstract
The antibacterial activity of Capparis spinosa L. extracts obtained from
Baghdad was evaluated against six clinical bacteria isolates of Helicobacter
pylori. The results presented in this work demonstrated that the leaves extract
showed a significant effect against bacteria as compared to the root and fruit
extracts at 100 mg/ml concentration, with inhibition zone ranging from 12.0 to
30.7 mm in each bacteria strain. The end results of GC-MS analysis indicated
that the ethanol extracts of caper have a lot of active chemical compounds,
including twenty-five, eighty-two and sixty-eight phytoconstituent
compounds, that are distinguished in the extracts of roots, leaves and fruits
with C. spinosa L. respectively. In addition, the high area % revealed in each
extracts were: 1-methyl-pyrrolidine-2-carboxylic acid 35.77%, prolin, Nmethyl-,
butyl ester 12, 63% and (23S)-ethylcholest-5-en-3.beta.-ol 19.12%
respectively.
Baghdad was evaluated against six clinical bacteria isolates of Helicobacter
pylori. The results presented in this work demonstrated that the leaves extract
showed a significant effect against bacteria as compared to the root and fruit
extracts at 100 mg/ml concentration, with inhibition zone ranging from 12.0 to
30.7 mm in each bacteria strain. The end results of GC-MS analysis indicated
that the ethanol extracts of caper have a lot of active chemical compounds,
including twenty-five, eighty-two and sixty-eight phytoconstituent
compounds, that are distinguished in the extracts of roots, leaves and fruits
with C. spinosa L. respectively. In addition, the high area % revealed in each
extracts were: 1-methyl-pyrrolidine-2-carboxylic acid 35.77%, prolin, Nmethyl-,
butyl ester 12, 63% and (23S)-ethylcholest-5-en-3.beta.-ol 19.12%
respectively.
Keywords
Antibacterial
Capparis spinosa
ethanol extracts
Gastric Ulcer
Helicobacter pylori