Al-Mustaqbal Journal of Pharmaceuticals and Medical Sciences

Background: Despite the critical role nurses play in managing poisoning cases, gaps in their knowledge can hinder
patient outcomes. An educational program may address this deficit, but its effectiveness on nurses’ knowledge in
poisoning management remains to be systematically evaluated.
Objectives: This study aimed to examine the effect of an educational program on nurses’ knowledge of poisoning
management.
Methods: A quasi-experimental study with a pre- and post-test design was conducted on 80 nurses working in an
emergency department (ED) in Al-Q¯ adisiyyah Governorate, Iraq. The 80 nurses were randomly allocated into two groups
of 40 to either receive the educational intervention or serve as a control group. Nurses in the intervention group received
three sessions of educational lectures over three consecutive days while the control group received no training. A 20-item
questionnaire was used to assess nurses’ knowledge of poisoning management at baseline and two months after the end
of the intervention. Descriptive statistics, chi-square, Fisher’s exact test, t-test, paired t-test, and analysis of variance
were used to analyze the data.
Results: At baseline, the intervention and control groups did not significantly differ in their mean knowledge scores
(1.36 0.13 vs. 1.40 0.12, P 0.172). The intervention group’s knowledge score increased to 1.91 0.05 after the
intervention (P < 0.001), while the control group’s score did not change significantly (P 0.08).
Conclusion: The educational program could significantly increase nurses’ knowledge of poisoning management.
Therefore, it is recommended that similar educational programs be held on a regular basis to improve emergency nurses’
knowledge and update them on how to handle poisoning cases.

Complexes containing Nickel, Copper, and Zinc salts were prepared and studied in this study. Additionally, novel
Schiff Base ligands were synthesized by reacting 6-aminopenicillinic acid with benzoyl isothiocyanate to produce L. The
synthesized ligand was evaluated by physical measures and spectroscopic methods such as Fourier transform infrared
spectroscopy, nuclear magnetic resonance, ultraviolet-visible light, mass spectroscopy, and micro elemental analysis.
Metal salts of (Ni(II), Cu(II), and Zn(II)) were combined with novel ligands at a molar ratio of 1:2 [M:L] to prepare the
complexes. Spectroscopic, magnetic susceptibility, molar conductivity, atomic absorption, and DTA methods were used
to study the complexes that were prepared. The-lactam ring complexes exhibited coordination with the central metal
ion through the N-atoms of the azomethine group and the O-atoms of the carbonyl group, leading to the formation of the
resulting octahedral hybrid form, which was denoted as Sp3d2.Experiment on the biological activity of each ligand and
its complexes against two bacterial species (S. aureus and P. pseudomonas), and find that all of them are more active
than the starting materials.

Theprimaryobjectiveofthisstudyistoassessthelevelofpatients’ understanding oftheeducationalprogramfollowing
cholecystectomy. Additionally, the study attempts to determine the correlation between patients’ knowledge and their
socio-demographic factors. A quasi-experimental design study was conducted at AL Imam Sadiq Teaching Hospital. The
study employed a non-probability selection method, namely selecting 30 patients for the study group and 30 patients for
the control group. The instrument consists of 14 items. The validity of the questionnaire was assessed by a panel of 11
experts. The reliability of the questionnaire was determined by calculating the Alpha Correlation Coefficient to measure
the instrument’s internal consistency, resulting in a value of (number). The data was analyzed using descriptive and
inferential statistical analysis methods. The study revealed that the patients’ level of knowledge in the pre-test was 1.20
for the study group and 1.18 for the control group. In the post-test, the study group had a knowledge level of 1.79, while
the control group had a level of 1.25. Furthermore, there was a significant statistical correlation between the patients’
employment, level of education, and monthly income, and the effectiveness of the instruction program in improving
patient knowledge. The instructional program had a beneficial impact on patients who underwent cholecystectomy,
leading to a significant improvement in their dietary knowledge compared to both the case and control groups.

Back ground: Proper placental development is essential for a successful pregnancy. An important organ, the placenta
carries out several physiological, immunological, and endocrine functions. It also performs vital roles in mediating the
exchange of gasses, nutrients, and waste products between the fetal circulation and the physically separate mother
circulation.
Aims: The purpose of the study was to evaluate how placental maturity affected the outcomes of pregnancies in
Babylon City.
Setting and design: A Babylon City private clinic, a purposefully selected sample of one hundred pregnant patients
who received a diagnosis at the private clinic.
Method, material: from medical records, ultrasound scan data, and the creation of a study tool specifically for this
investigation.
Statistical analysis used: The Statistical Package for Social Sciences (SPSS-20) was used to perform descriptive
statistics and correlation analysis on the data. Findings: Of the women who gave birth, 62% had cesarean sections.
Preeclampsia, severe preeclampsia, chronic hypertension, and gestational hypertension accounted for 87% of the
participants with pregnancy-induced hypertension, while anemia affected 93% of the participants. Among newborns,
80% required resuscitation, 68% were delivered via cesarean section, and 87% were IUGR.
Conclusions: According to the study’s findings, 85% of women were between 36 and 39 weeks gestation. Placental
grade was correlated with gestational age, resuscitation, stillbirth, gestational hypertension, and the meconium.

Diclofenac, potent a nonsteroidal anti-inflammatory drug, used in the treatment of inflammation, pain and fever
associated with a wide range of disease condition. This review article focuses the synthesis, mechanism of action,
pharmacokinetics and derivatives of diclofenac and also highlights advances in the possible use of diclofenac in treating
other condition outside its current clinical therapeutic use as an analgesic, anti-inflammatory and antipyretic agent as
well the prospect of drug repurposing of diclofenac for treatment of disease like cancer. It further highlights the adverse
effect of the drug as an emerging contaminant in the environment. Diclofenac acts by inhibition of COX enzymes and
subsequently reduces the synthesis of prostaglandins, the predominant prostanoid produced in inflammatory processes.
Diclofenac is primarily metabolized in the liver and is eliminated in the urine and bile as conjugates of diclofenac and
its metabolites. Despite its effectiveness in management of pain, inflammation and fever, there are reports of adverse
gastrointestinal, cardiovascular and renal effect resulting from its systemic use, suggesting the need for more research
on its drug modification in order to reduce or eliminate the adverse effects. Research suggests that diclofenac has
antimicrobial, anticancer and neuroprotective property. As an anticancer agent, research suggests diclofenac exhibit
anti-proliferative and apoptosis mediating property. Diclofenac arrest cell cycle, thus preventing proliferation of neural
stem cells, glioblastomas, ovarian cells, osteoblasts, human lymphatic endothelial cells, and vascular smooth muscle cells
and induces apoptosis of neuroblastoma cell, this project this drug as a novel prospective anticancer agent. However,
its adverse environmental effects as an emergent contaminant still remains a source of concern.