Al-Mustaqbal Journal of Pharmaceuticals and Medical Sciences

Background: Anemia is a global public health problem affecting developed and adversely affecting developing coun
tries. About 1.62 billion peoples are affected worldwide, currently pregnant women are the most vulnerable population
corresponding to 24.8%. Objective: To evaluate RBC indices and significance of Mentzer index for differentiation
between Iron deficiency anemia and Beta thalassemia trait. Patients and methods: Cross sectional study was conducted
in Babylon Maternity and Pediatrics Teaching Hospital for a period of 4 months. Data was collected prospectively
after approval of the research proposal was gained, the study involved 114 patients that were referred to the Babylon
Maternity and Pediatrics Teaching Hospital. Results: The average age of IDA patients was 11.79 6.09, while that of
BTT patients was 12.15 5.26. There was no significant relationship between the mean age of patients with illness.
Those with a Mentzer Index greater than 13 are more likely to have IDA (sensitivity 95.6%) and less likely to have beta
thalassemia (specificity 95.6%). Patients with a Mentzer Index <13 are more likely to have TT (sensitivity 72.7%)
and non-probability of IDA (specificity 72.7%). Conclusion: Clinicians face a dilemma distinguishing between iron
deficiency anemia and beta thalassemia in anemic patients since diagnostic tests are not inexpensive to the majority
of the population. The Mentzer Index can be used as a screening test for iron deficiency anemia, with sensitivity and
specificity of 95.6% and 72.7%, respectively, and for beta thalassemia. Those with a Mentzer Index <13 can undergo
Hb electrophoresis for confirmation.

Background: Assessing the effectiveness of a nurse-led family-focused program on the physical health domain of
children with congenital heart defects (CHDs) is a critical area of research. CHDs are among the most common congenital
anomalies, affecting nearly 1 in 100 live births. physical activity plays an important role in overall health and recovery
congenital heart disease. Quality of life educational include specific directions to increase level of physical activity, such
as walking daily or exercising regularly.
Objectives: This study aims to assess the effectiveness of a nurse-led family-focused program in improving the physical
health outcomes of children with CHDs.
Methods and Results: A quasi-experimental design to investigate the impact of an educational program on the
physical health domain for children with congenital heart defects. Purposive sampling technique which is type of non
probability sampling methods sample of (60) participants was randomly divided into two groups of 30. The study group
havebeenexposedtotheeducationalprogramforthechildrenwithcongenitalheartdefects bytheresearcher. Moreover,
the control group follow the traditional program provided by the Heart Center.
Results: The results show statistically significant differences between two groups. Enhancement of the physical
health among the study group during the period of measurement. Appling of the educational program for children
with congenital heart defects program effect positively on children with CHDs.
Conclusion: The nurse-led family focused program to improve the physical domain of children with congenital heart
defects program has improved physical health in those children who parents attended program.

New derivatives of imides 1,2,4-triazole polymers as pharmaceutical compounds were prepared from the synthesis of
amic acid compounds (1A-E) by reacted of benzocaine with different cyclic anhydrides. Then cyclic imide compounds
(2A-E), which prepared from converted amic acid compounds by using acetic anhydrate (CH3CO)2O and anhydrous
sodium acetate CH3COONa as a water drawer agent. Compounds (2A-E) were react with nucleophilic addition of
hydrazine hydrate to ester cyclic imide compound to produce acid hydrazide cyclic imide compounds. Thereafter,
cyclization of compounds (4A-E) and (5A-E) were prepared from react of acid hydrazide cyclic imide compounds with
poly acryl amide via microwave to give imides 1,2,4-triazole polymers (4A-E) and in other path acid hydrazide cyclic
imide react with poly acrylonitrile via microwave to give imides 1,2,4-triazole polymers (5A-E). All prepared compounds
were characterization by physical properties such as melting point, softening point and analytic technique like FT-IR,
1H-NMR for some of them, the compounds were tested anticancer and antibacterial applications were studied.

Brain tumor classification is one of the crucial uses of medical image processing. A longer life is possible if the
tumor is correctly and promptly diagnosed. Because manually segmenting brain tumors for cancer diagnosis is difficult
and time-consuming, automatic classification of brain tumor images is necessary for this task. Pre-processing, feature
extraction, feature selection, and classification are the four stages of the general framework for automatic tumordetection
from MRI images. The method for automatic brain tumor classification described in this research combines machine
learning and deep learning algorithms. We used three pre-trained deep networks to extract the most detailed information
from MRI images. ResNet, AlexNet, and GoogleNet are the networks that were utilized for feature extraction for the
diagnosis of brain tumors, the classification model has been a support vector machine (SVM). Additionally, in this
research, the best feature vector was chosen using the MRMR algorithm to improve classification speed and accuracy.
The BRATS database is used to provide the training dataset. The BRATS validation dataset showed promising results
for the investigated method. This method’s complete tumor classification accuracy on experimental data is 99.5% on
average in this dataset.

The research aims to find out the effect of rehabilitation exercises and antioxidants in some physical and physiological
abilities, free radicals and the degree of pain for patients with stable heart failure, and the research sample was selected
randomly and whose ages ranged between 40–45 years and their number is 30 female patients with this disease, and
the researcher used the experimental approach as the most appropriate approach to solve the research problem, as the
sample was divided into two groups equal in number, each of which (15) patients (experimental and control), and the
tribal tests were carried out after That the procedures were explained to the participants and their approval was obtained
officially on 15/9/2024 and the post-tests were on 1/12/2024 at the Kings Hall for Women in Babylon Governorate, It
included physical tests (heart stress test) and the physiological tests included cholesterol test, which included (benign and harmful cholesterol), heart rate, pulmonary ventilation, high and low blood pressure, free radicals and the degree of pain and the researcher concluded that rehabilitation exercises and antioxidants that are given regularly in sports halls and under the supervision of specialists affect the above variables.