Abstract
It is a common and potentially serious infection of the liver that results in significant morbidity and mortality caused by hepatitis B virus. Hepatitis B is spread predominantly by the parenteral route or by intimate personal contact. During the incubation period, HBsAg, HBeAg, and HBV DNA become detectable in serum and rise to high titers. The highest rates of HBsAg carrier are found in developing countries with primitive or limited medical facilities. Identifying the Epidemiology of Hepatitis B virus infection among blood donors and families of infected donors. A cross- sectional study was conducted on ( 2408) blood donors and (324) persons of the
members of family of some positive cases through the period extended from the first of May 2006 up to the end of December 2006, in Main Blood Bank Centre in Tikrit Teaching Hospital and in Public Health Laboratory of Saladdin Health Office. The information was obtained from the positive cases and their families by the researcher according to prepared questionnaire. All blood samples are screened for the presence of HBsAg by enzyme-linked immuno-sorbent assay (ELISA) technique, using Biokit, S.A. Barcelona-Spain (bioelisa HBsAg colour). The prevalence of positive cases among blood donors was (3.49%) while the prevalence among infected cases
family members was (10.19%). The cases were increase proportionally with increasing in age. The Hepatitis B carrier cases were higher among male(3.4%), rural (4.55%), married (3.9%), illiterates (4.56%) and those with history of surgery(4.2%) but the differences for all previous were of no significant while among those with a history of blood transfusion(4.23%), the result was statistically significant . regarding the positive cases among family members of positive blood donors, The carriers were higher among siblings (6.22%). The prevalence of positive cases among blood donors were increase proportionally with increasing in age and among those with a history of blood transfusion ,the result was statistically significant in addition to that the
prevalence among infected cases family members was more frequent among siblings.
members of family of some positive cases through the period extended from the first of May 2006 up to the end of December 2006, in Main Blood Bank Centre in Tikrit Teaching Hospital and in Public Health Laboratory of Saladdin Health Office. The information was obtained from the positive cases and their families by the researcher according to prepared questionnaire. All blood samples are screened for the presence of HBsAg by enzyme-linked immuno-sorbent assay (ELISA) technique, using Biokit, S.A. Barcelona-Spain (bioelisa HBsAg colour). The prevalence of positive cases among blood donors was (3.49%) while the prevalence among infected cases
family members was (10.19%). The cases were increase proportionally with increasing in age. The Hepatitis B carrier cases were higher among male(3.4%), rural (4.55%), married (3.9%), illiterates (4.56%) and those with history of surgery(4.2%) but the differences for all previous were of no significant while among those with a history of blood transfusion(4.23%), the result was statistically significant . regarding the positive cases among family members of positive blood donors, The carriers were higher among siblings (6.22%). The prevalence of positive cases among blood donors were increase proportionally with increasing in age and among those with a history of blood transfusion ,the result was statistically significant in addition to that the
prevalence among infected cases family members was more frequent among siblings.
Keywords
blood donors
Epidemiology
HB V