Abstract
New octahedral complexes of (L1)N-(pyridin-2-yl)-1-(pyridin-4-yl)methanimine derived from (4-Pyridinecar boxaldehyde and 2-Aminopyridine) with the following metal ions Mn(II), Co(II), Ni(II), Cd(II), and Hg(II) were synthesized in ethanol. The ligand and its complexes are characterized by 1H NMR, FT-IR, 13C NMR, UV.Vis, chloride content, atomic absorption, magnetic susceptibility measurements, elemental microanalysis, thermal analysis, molar conductivity, mass spectroscopy, X-ray diffraction, dimensional measurements. Nanoparticles in the scanning electron microscope (SEM), which was used to characterize nanocomposites. After evaluating the antibacterial and antifungal properties of the compounds against two different types of bacteria (Gram-positive (G+) bacteria Staphylococcus aureus and Gram-negative (G-) bacteria Escherichia coli and one type of fungus (Candida albicans), the results indicated that the antibacterial activity The antimicrobial activity of the complexes is superior to that of the free compound. As for the biological activity of the nanocomposites, it indicates that the prepared complexes have the ability to inhibit the growth of Gram-positive and negative bacteria and Candida fungi in varying proportions, and that the biological activity of the prepared compounds has a greater inhibitory ability because they have nanoscale properties represented by an increase in the exposed surface area. Due to its interaction and small size, which makes it more effective than complexes and ligands.
Keywords
4-pyridinecarboxaldehyde
nanocomposites
Schiff bases