Abstract
Background: Bees naturally create propolis from plant exudates mixed with pollen, wax, and enzymes. It has anti-inflammatory and antibacterial qualities well-known. Adhering firmly to the surfaces of teeth and other complicated structures in the mouth, plaque is a yellowish white or greyish material. The study aimed to assess how lozenges including propolis affected Interleukin-10 (IL-10) levels and plaque development. Method: This study was a Prospective Interventional Controlled Clinical Trial. A total of eighty volunteers were divided into two groups 40 in the study group and 40 in the control group. Following a baseline saliva sample collection, study group volunteers received oral hygiene instruction plus propolis lozenge extract; the Plaque Index was then calculated. Over seven days, they were asked to use the lozenge twice daily, once in the morning and once in the evening. The control group, on the other hand, got just oral hygiene instructions (The importance of dental health and its effect on the overall body, the relevance of daily brushing and flossing, and the avoidance of cariogenic diet). During the second visit, saliva samples were collected again, and the Plaque Index (PI) was measured. Result: The study group observed significant differences between the two visits regarding the mean Plaque Index (PI), whereas the control group did not show significant changes. Additionally, significant differences were found in the mean levels of interleukin-10 in the study group.
Keywords
Anti-bacterial
anti-inflammatory
interleukin-10
lozenges
plaque
Propolis