Abstract
Ginger is a medicinal and nutritional plant characterized by its rich composition of bioactive compounds. It contains approximately 40 antioxidant and anti-inflammatory compounds, including phenols. Therefore, the current study aimed to evaluate the antioxidant efficacy of ginger\'s alcoholic extract and to estimate its phenolic compound content. The alcoholic extraction of ginger root was performed by soaking it in 70% ethanol. Using DPPH and ABTS assays, the antioxidant activity of the plant extract was evaluated in vitro. The total phenolic content was estimated using the Follin-Cioalto method, and IC₅₀ values were calculated based on dose-response curves. Our results indicate that the alcoholic ginger extract exhibited concentration-dependent antioxidant activity in both the DPPH and ABTS assays, the highest concentration (400 micrograms/ml) recorded inhibition rates of 82.2% in the DPPH and 87.8% in the ABTS.
IC₅₀ values were recorded at 93.6 ± 3.9 µg/mL for the DPPH assay and 79.2 ± 3.3 µg/mL for the ABTS assay, reflecting the extract\'s higher efficiency in neutralizing the ABTS free radical. The total phenolic content yielded 78.5 ± 2.7 mg gallic acid equivalent/g dry weight, indicating the major role of phenolic compounds in the antioxidant activity. These results, taken together, indicate the potential use of ginger root extract in food and pharmaceutical applications and confirm that it is a promising natural source of antioxidants.
IC₅₀ values were recorded at 93.6 ± 3.9 µg/mL for the DPPH assay and 79.2 ± 3.3 µg/mL for the ABTS assay, reflecting the extract\'s higher efficiency in neutralizing the ABTS free radical. The total phenolic content yielded 78.5 ± 2.7 mg gallic acid equivalent/g dry weight, indicating the major role of phenolic compounds in the antioxidant activity. These results, taken together, indicate the potential use of ginger root extract in food and pharmaceutical applications and confirm that it is a promising natural source of antioxidants.
Keywords
ABTS
antioxidant
DPPH
Ginger
Phenols