Muthanna Medical Journal

The assessment of autoantibody before clinical onset of Rheumatoid Arthritis, has been helped
in establishing early diagnosis. Recent studies on RA described many inflammatory conditions
that precede joints inflammations. Anti-CCP and IgM-RF were evaluated in 10-RA patients
and in same number as control. Anti-CCP was detected by ELISA and IgM-RF using latex
agglutination test, while the CRP was measured by latex turbi-imetric immunoassay, and the
ESR was measured by Westergren method. The values of Anti-CCP antibody is more sensitive
than the other tests, in 50% were positive, and 50% negative. CRP measures were fluctuated
around 37% positive and 63% were negative. ESR values have been shown a significant
increase in 90% positive, whereas 10% negative. RF show a significant increase by 60%
positivity. The positive value was higher for anti-CCP antibodies in comparison to other
markers for RA patients. Interestingly, there were not significant relation between anti-CCP
antibody titers and inflammatory markers such as ESR and CRP. However, there is a tighten
relation between Anti-CCP and RF had been confirmed.

The aimed of this study is identified the BM changes that associated with (CRF), especially in
those patients, treated with the recombinant erythropoietin and secondly how was the
hematological response to erythropoietin itself. We followed 75 uremic patients whom were
on (RDP) and were treated with a recombinant erythropoietin and supplemented by a parenteral
iron because of symptomatic anemia, by bone marrow biopsy through anterior superior an iliac
crest approach. All the specimens had been submitted to a histopathological examination by
the same well certified pathologist. We found that 50 patients (66.66%) were males and 25
patients (33.33%) were females. Regarding the BM biopsy results 35 patients (46.66%) got
(EH) 30 patients (40%) got normal cellular BM 10 patients (13.33%) got hypoplastic BM.
There was no evidence of granuloma, carcinoma, sclerosis osteomalacia or osteoporosis in any
of our patients. Regarding the response to erythropoietin, we found that most of our patients
got a frequently symptomatic anemia and needed a blood transfusion irrespective of the regular
(HD) that was supplemented by erythropoietin with a parenteral iron. We concluded that there
was no specific BM changes that can be attributed to CRF. As far as the matter of erythrpoietin
therapy was concerned, we found that most of our patients were still in a real need for a blood
transfusion because of the symptomatic anemia irrespective of the erythropoietin
administration in addition to parenteral iron. So we think that we must search for other
modalities of therapy for the anemia in CRF in addition or an alternative to erythropoietin
which had not reduced remarkably the need for the blood transfusion in our patients.

25 patients, 20 male patients and 5 female patients with knee joint injury, all of them with
single knee joint injury. 25 knee joints are examined during this study, all patients are perform
MRI in different centers send with report of the MRI from expert radiologist. They perform
arthroscopy in Al Sadder medical city from January 2013 – October 2014. The aim of this
study is to confirmed or unconfirmed ACL injury after clinical examination and MRI which
they perform to them either in our center or other centers. The majority of ACL injuries 70%
occur while playing agility sports, and the most often reported sports are football. About 70%
of ACL injuries are sustained through noncontact mechanisms, while the remaining 30% result
from direct contact. The aim of this study is to assess the diagnostic value and compare the
accuracy (sensitivity and specificity) of MRI to arthroscopic finding regarding the ACL injury.