Journal of Basrah Researches (Sciences)

Several studies have shown that high oxidative stress levels are associated with haemodialysis (HD) . Glutathione S- transferase ( GSTM1 and GSTT11) are members of the GST family of proteins , which protects cellular DNA against oxidative damage . This study tested the association of GSTM1 and GSTT1 gene polymorphism with some physiological parameters among haemodialysis patients.

Ninety, one old local duckling that weighed 50 g were randomly divided into 3 groups with 3 replicates per treatment. The aim of this study was to investigate the influence of increased vitamin A levels on the production performance, some physiological traits and histological characteristics . Supplemental levels were: 4000, 8000 IU and 0 vitamin A dissolved in sunflower oil was given directly into the mouth via syringe for twice during the first week after hatch . Vitamin A levels had no significant (P<0.05) effect on feed intake and relative heart and liver weight . Supplemented with 8000 IU vitamin A increased the body weight and weight gain significantly (P<0.05) and improved feed conversion ratio more than supplemented with 0 IU vitamin A . The influence of vitamin A 8000IU on hemoglobin concentration , PCV and erythrocyte count was significantly increased (P <0.05) (P<0.01) respectively at 7 weeks of age. But had no significant (P<0.05) effect on the percentage of lymphocytes , granular and monocytes cells . In addition, vitamin A had no significant (P<0.05) effect on serum thyroxin hormone , glucose and cholesterol levels . Histological study showed that villi height , crypt depth were increased as vitamin A supplement increased (4000 , 8000 IU) . In conclusion, feed supplemented ducks with 8000 IU vitamin A led to better growth rate and better performance of local ducks.

In this paper, an algorithm for solving nonlinear unconstrained optimization problem by combining extended Conjugate Gradient (CG) and the damped-technique of Powell for the method to the Broyden family of quasi-Newton method is proposed . The basic idea is to choose a combination of the damped-technique of Powell and some pervious search directions using inexact line search as new search direction. We show that the global convergence for the new methods is possible and present, in particular. The global convergence property of the new algorithm is investigated under few weak conditions.

. In the present study, a labor has been made to develop gel type of transdermal therapeutic system comprising different concentrations of metronidazole with hydrophilic polymeric combinations using solid dispersion method. Two main parts including chemical and biochemical were discussed in this study. In the chemical part, In vitro drug release and kinetics of drug release were studied for all the prepared pharmaceutical formulations in this study. The prepared formulations including G3 and H3 followed zero order, Korsmeyer-Peppas model and Fickian (n<0.5) transport mechanism (diffusion controlled release). In the biochemical part, the biochemical activities of all the prepared formulations (as antimicrobials) were studied (in vitro) in four types of microbes including Staphylococcus aureus (Gram-positive), Staphylococcus epidermidis (Gram-positive), Candida albicans (yeast) and Trichophyton sp. (mold) by using agar diffusion method. These formulations showed an increase in their biochemical activities against these isolates and these activities an associated with the increase in drug concentrations which were loaded with the selected polymers in this study and in addition to their possession of highest antimicrobial and biochemical activities to inhibit the growth of these microbial isolates as compared to pure drug and commercial gel at (p<0.05). Also, the prepared formulations including G0, G3, H0 and H3 were applied (in vivo) to the skin of male rabbits for studying subacute toxicity test (LD50), skin (back and rectal) irritation tests and the created skin irritation treatment test. These formulations were not poisonous and non irritant, while H3 formulation possessed of ability to treat the created skin irritation during (10-12) days. . .

The Charge Transfer complexes(CTC) between 7,7,8,8-tetracyanoquinodimethane (TCNQ) and some tellurium compounds have been investigated spectrophotometrically in the UV-Visible region. The values of energies of transition , ionization potential (IP),and the dissociation energies of charge transfer (CT). complexes excited state(w) of these complexes have been calculated and were in the range of 9.96 - 9.35 ev.
The charge transfer parameters of the tellurium compounds as a donor with TCNQ as accepter which is represented by ECT. ,KCT. ,Δ G وΔ H, and Δ S ,have been estimated .The data was analyzed using Bensi- Hildebrand equation ,from which the formation of 1:1 charge transfer complex was concluded.

In order to increase the processing speed of online learning applications represented in its exigent requirement of reducing the amount of Support Vectors, this paper is devoted to present a durable algorithm to construct the well-known Support Vector Classifier, by capturing a unique Vector from each class of training instances. We called that Vector the (Golden Support Vector).
Our algorithm had adopted basic mathematical tools for its constructional phases. The algorithm starts with applying its Hybrid Enclosing Mechanism in order to enclose two sets of mapped instances (Vectors) with the most optimistic non-overlapped curved spaces analogous to the instances distribution. This mechanism is considered as a spring point that leads us directly to separate these spaces with a Strong Separating Hyperplane. From both sides of that Hyperplane, two parallel Supporting Hyperplanes will be released settling down on the first detected Vector, which we called the Golden Support Vector. Each Supporting Hyperplane with its acquired Golden Vector is considered to be the basis to construct the edges of Maximal Margin of Separation Space; which offers best generalization ability not only to the trained instances but also to guarantee high predictive test accuracy for future instances from the same distribution

Schiff bases were prepared via direct fusion (solvent free) of vanillin with P- Toluidine , 2, amino-4, 6-dimethylpyridine. Indole-3-carboxaldehyde with o-aminophenol , P- Toluidine and 2, amino-4, 6-dimethylpyridine.
The synthesized compounds has been characterized on the bases of IR and 1H NMR spectra. The study reveals that the method is simple and takes a short time in addition it is a simple method of purification in a moderate yield.

A numerical study of the effect of injection current modulation on the dynamics of a quantum dash semiconductor laser is presented . The control parameters chosen to affect the temporal intensity variation are the gain , the dc and ac parts of the injection current , the modulation frequency ,carrier escape rate and ratio of carrier to photon decay rates . Various output ranging from single pulses to chaotic one produced.

Several dynamics of directly modulated InAs/InGaAs quantum
dot semiconductor laser in the presence of optical feedback have been studied extensively. The effect of feedback strength,linewidth enhancement factor, dc bias strength of the injection current, the modulation strength and modulation frequency are studied. Various types of dynamics ranging from periodic to chaotic ones are seen to occur. Coherence collapse (output drop out) occurs as a result of choosing certain combinations of the control parameters appeared in the theoretical model.

The current study were included one hundred and twenty blood sample with draw form patients with allergic asthma , they were selected randomly from the Allergy and Asthma Center in Basra city and there were eighty sample with draw from healthy individual as control . All samples from patients and controls were tested by direct ELISA for total IgE and Polymerase chain reaction was performed to detect a genetic relationship between allergic asthma and human leukocyte antigen classII allele (HLA- DQA1 and HLA- DRB1 alleles).Result of this study showed that the total IgE>100 IU/ml had higher rate in asthma patients at (70.8%).with significant difference( p<0.05) between total IgE<100 IU/ml and controls. The study also included detection of some human leukocyte antigens (HLAclassII) alleles HLA DRB1*0101/2/4 , HLA DQA1*0401, HLA DQA1*0101/4 by the use of PCR analysis to determine their impact on the asthma allergy. The results of this analysis revealed the HLA DQA1*0401 had higher rate at(89.2%) in asthma patients ,also this allele appeared in 100% of asthma patients who had total IgE>100 IU/ml . All studied HLA class II alleles were significantly (P<0.05) distributed in the study groups .

The study included the measurement of the mean serum uric acid level in asthmatic patients. In this study, a total number of (50) asthmatic patients (24 males, 26 Females) visiting Allergic and Asthma Medical Center in Basrah city were involved, classified according to age, sex, severity, smoking and family history. From each patient blood samples were collected to estimate uric acid concentration. In addition, (50) healthy subjects were investigated as a control group.
It was found that a highly significant increase (P < 0.01) is in uric acid serum level in all asthmatic patients as compared to healthy control. In accordance with age and severity, serum uric acid level increases significantly (P < 0.05) while with smoking patients, and positive family history a highly significant increase is (P < 0.01). There were no significant changes in the uric acid level between males and females.
In conclusion, asthmatic patients suffer a high degree of reactive oxygen species (ROS) formation causing considerable oxidative stress indicated by a high level of the serum uric acid.

A new geminisurfactant polyamide derived from Hexamethylenediamine (HMDA) and ethylenediamintetraaceticacid (EDTA) 2,2'-(1,2-diamino-8,15-dioxo-7,10,13,16-tetraazadocosane-10,13-diyl) diacetic acid was synthesized and characterized by FTIR and NMR. A series of electrochemical measurements, including corrosion potential and corrosion current has been made on polyamide-coated carbon steel samples in corrosive environment. Results showed that polyamide can offer some degrees of protection in the corrosive environments.The corrosion study of this polymer outline that a new surfactant has a good resistanace to the corrosion of carbon steel in 0.1 Msolution of HCl, which can indicate to uses as anti-corrosion materials.