Muthanna Medical Journal

Thyroidectomy is one of the common operations performed worldwide. It is a main option of
treatment for different benign and malignant thyroid problems. Despite improvements in
procedures have decreased mortality and even and morbidity rates to a minimum; however,
postoperative complications remain a major concern among surgeons. We aimed to evaluate the indications and complications of thyroidectomy. A Prospective study was conducted at AlRamadi Teaching Hospital/Ramadi city/Iraq during the period from January 2009 to January 2010. There were 130 patients underwent thyroidectomy. A demographic and clinical data for each patient was recorded to assess indications and complications of different types of thyroidectomies. The majority of the patients were females (93%). The most age group affected was 21-30 years (41.54%). Pressure symptoms were accounting for 61.54% of the indications. Thyroid enlargement in euthyroid states (80%) was the common presenting state. Subtotal thyroidectomy (58.46%) was the commonest procedure. Out of 130 patients, 36 patients (27.69%) were suffered from complications. The 2 most common complications encountered in the study were hypocalcemia (61.11%) and recurrent laryngeal nerve palsy (5.38%). In conclusion, subtotal thyroidectomy is a common procedure in our hospital. Compressive complaints were the most common indication. Hypocalcemia and recurrent laryngeal nerve palsy were the 2 most postoperative complications.

Alopecia areata (AA) is lost hair from a few or all regions of the body, for the most part from
the scalp. Etiology and pathogenesis of alopecia areata being not totally comprehended, is
accepted to be multifactorial in ancestry. Recently, studies suggested an association between
alopecia and types of viruses, therefore we concerned to investigate the association between
CMV infection and alopecia areata. This study included of 100 individuals (50 alopecia patients
and 50 healthy). Mean age of study groups were 20.90 ± 11.07 and 22.64±12.29 years of
cases and control group respectively. Mean of age onset of patients were 20.83 ± 10.0. Out
of 50 patients 52% were male, the rest were female. However, 1:1 of control group was male:
female. 40% of patients had a positive family history for this disease. Alopecia areata affected
on scalp in 78% of cases. All patients had a high concentration of CMV IgM. With treatment
of oral ganciclovire drug, a decrease of anti-CMV IgM levels and an increase of CMV IgG
levels were observed.

Platinum analogs includes cisplatin, oxaliplatin and carboplatin. Cisplatin is a chemotherapeutic drug with excellent success in the management of human malignancies. Molecular mechanism of action related to its capacity to crosslink of DNA purine bases; also, by interfere with DNA repair, leading to DNA break, and consequently lead to apoptosis in cancer cells. Cisplatin also found to have immunomodulatory properties besides its cytotoxic effect.