Abstract
Background: Toxoplasma gondii is the most common infection of proto-
zoa, affecting a wide range of hosts. Toxoplasmosis is usually asympto-
matic in immunocompetent persons, but in immunocompromised persons
(ex:patients on dialysis) significant problems can ensure, and may pro-
gress to a life-threatening infection.
Objective: To investigate the seroprevalence of anti-Toxoplasma antibod-
ies in patients undergoing hemodialysis in Baquba / Iraq .
Patients and Methods: A group of blood samples, consisting of 75 dialy-
sis patients and 50 healthy controls, were examined for the detection of
anti-toxoplasma antibodies in Baquba Governorate from November 2020
to April 2021 using enzyme-linked immunosorbent assay (ELISA) for IgG
and IgM.
Results: The total numbers of the 125 samples were examined, 32 (44.0%)
and 2 (4.0%) were IgG-positive for both patients and healthy individual re-
spectively, and the results of the current study showed only 1 (1.33%) was
seropositive IgM for patient group, while no seropositive healthy subjects
was found for IgM . The results showed that the percentage of seropositivity
was higher in 17 males (40.47%) than in females 15 (45.45%) in the group of
patients, but the differences were not statistically significant . As for the age
groups, a positive increase was observed in the age group 11-30 years when
comparing patients and healthy people, as the percentage reached 5
(29.41%). It was also observed that the highest seropositivity in the educa-
tion levels was in the group of patients at the educational level 6-12
(45.45%) than in the healthy controls group, but the differences were not sta-
tistically significant between education levels. Patients living in urban areas
had significantly higher serum (P = 0.0041) than patients in rural areas, and
the odds ratio was 22,000. And those who had contact with cats showed a
significant increase in seropositivity p = 0.0466 and odds ratio was 20.5789.
Conclusion: Dialysis patients are at risk for toxoplasmosis and should be
screened on a regular b
zoa, affecting a wide range of hosts. Toxoplasmosis is usually asympto-
matic in immunocompetent persons, but in immunocompromised persons
(ex:patients on dialysis) significant problems can ensure, and may pro-
gress to a life-threatening infection.
Objective: To investigate the seroprevalence of anti-Toxoplasma antibod-
ies in patients undergoing hemodialysis in Baquba / Iraq .
Patients and Methods: A group of blood samples, consisting of 75 dialy-
sis patients and 50 healthy controls, were examined for the detection of
anti-toxoplasma antibodies in Baquba Governorate from November 2020
to April 2021 using enzyme-linked immunosorbent assay (ELISA) for IgG
and IgM.
Results: The total numbers of the 125 samples were examined, 32 (44.0%)
and 2 (4.0%) were IgG-positive for both patients and healthy individual re-
spectively, and the results of the current study showed only 1 (1.33%) was
seropositive IgM for patient group, while no seropositive healthy subjects
was found for IgM . The results showed that the percentage of seropositivity
was higher in 17 males (40.47%) than in females 15 (45.45%) in the group of
patients, but the differences were not statistically significant . As for the age
groups, a positive increase was observed in the age group 11-30 years when
comparing patients and healthy people, as the percentage reached 5
(29.41%). It was also observed that the highest seropositivity in the educa-
tion levels was in the group of patients at the educational level 6-12
(45.45%) than in the healthy controls group, but the differences were not sta-
tistically significant between education levels. Patients living in urban areas
had significantly higher serum (P = 0.0041) than patients in rural areas, and
the odds ratio was 22,000. And those who had contact with cats showed a
significant increase in seropositivity p = 0.0466 and odds ratio was 20.5789.
Conclusion: Dialysis patients are at risk for toxoplasmosis and should be
screened on a regular b
Keywords
Antibodies
Hemodialysis
IgG
Toxoplasma gondii