JOURNAL OF KUFA FOR CHEMICAL SCIENCES

The current study includes organic synthesis of some new pyrazol derivatives from 2-amino
thiazole by prepare diazonium salt from it with Ethyl Aceto Acetate as coupling compound to form
Azo compound (B). From this azo compound, pyrazol Derivatives are prepared by closing the Aceto
and Aster groups via hydrazine and phenyl hydrazine under Microwave irradiation respectively . The
other step is the preparation of Chalcone derivative(CH) from Azo compound (B) with p-N,N-di
methyl amino banzaldehyde. also pyrazol Derivative was prepared by reaction the Chalcone
derivative with hydrazine hydrate in acidic and basic medium . These compounds are identified and
confirmed by FT- IR, 1HNMR, 13CNMR.

This study included preparation and characterization of the chalicon compound that which prepared from
reaction terephthalaldehyde with 4-bromoasetopheone and also prepared a number of heterocyclic compounds from
the chalicon derivative with (Thiourea), (urea), (2,4-dinitrophenyl hydrazine),( 1,2-diamine-benzene) these
dreivatives are (Thiazine, Oxazine, Pyrazole, diazepine). All the prepared compounds were diagnosed by means of
the FT-IR spectra and the proton 1H.NMR spectra. Then the bio-activity of these compounds and their effect on two
types of bacteria (staphylococcus, Escherichia coli) were studied some compounds were identified that have a strong
inhibitory effect.

Abstract :This study includes preparing the new Azo compound (DH) Dissolved of 1,4- phenylenediamine in a mixture of Sodium nitrite ,concentrated hydrochloric acid and 4-hydroxyacetophenone then preparing the Schiff base (D) By reacting the prepared Azo with 2-aminoanthraquinone in the presence of drops from Glacial acetic acid ,via microwave method , the Synthesis of Imidazolidine derivatives (D1-D2) by reacting (D) with the amino acids Lucien and Tyrosine respectively, then react (D) with Maleic Anhydride and Phthalic Anhydride to Prepare the seven membered rings of Oxazepane (D3) and Benzoxazepene (D4) , respectively . The (TLC) technique was used to follow the reaction , iodine was used as a moderator, and after purification of the prepared derivatives the melting Points were measured. The infrared (FT-IR) spectra and The spectra of Proton NMR (1H NMR) .

The new Azo-Schiff ligand type N2O2 have been prepared through two steps. The first one Included the reaction between one equivalent of P-Phenoxy aniline and one equivalent of Salcyldehyde salcildihyde to prepare azo compound .and second step include the reaction of azo compound with tri ethylene tetra amine in order to prepare the new Azo-Schiff ligand. The ions metal of Zn+2, Cd+2 and Hg+2 with the new azo-Schiff ligand Complexes were prepared with mole ratio (1:1) (M: L) the prepared compounds were characterized by FT-IR, UV-Vis, while 1HNMR spectra were taken for the new ligand and it complex with mercury, Elemental analysis, as well as the molar conductivity and magnetic successptibility for all prepared complexes. These measurements showed that complexes of Cadmium and Zinc have octahedral shape, and tetrahedral for Mercury complex. The biological activity was evaluated against two kinds of bacteria, gram positive and gram negative for the new Azo-Schiff ligand and it's complexes with Zn+2 , Cd+2 and Hg+2 .

As a result of the industrial expansion and the increase in the population in Anbar Governorate, the sources of air pollution in it have multiplied, the most important of which are industries, various crafts, means of transportation, and residential, agricultural and commercial activities. The current study included estimating the element of lead through seventy selected stations throughout the governorate, including stations in agricultural areas that were considered standard in the study in order to make a comparison. The study indicated that the concentration of lead element in all areas of the study is relatively high, as well as that some study stations showed clear contamination with this element, as its concentration increased in the permissible limits in some countries and national determinants and the World Health Organization, and these stations were represented by some industrial, commercial, traffic, and stations Gasoline filling. The results of this study were compared with previous studies in Iraq as well as international studies. Some stations showed clear pollution with this element, as its concentration increased to the permissible limits in some countries, national determinants and the World Health Organization, and these stations were represented by some residential, commercial, traffic, and industrial areas and petrol filling stations, and the reason was the added lead to fuel.

In this approach, poly p-toluidine(PPT) was prepared based on the literature. The adsorption of carmine on the surface of poly p-toluidine(PPT). Different conditions affecting the adsorption process such as equilibrium time, initial concentration of studied dye , amount of polymer, and pH factor were studied. Isotropic experiments were performed and equilibrium adsorption data were fitted to the Langmuir and Freundliche isotherms. The thermodynamic and Kinetic study has also investigated the results that adsorption of carmine follow pseudo-second order. Also, the carmine was successfully extorted after adsorption. The morphology of surface was studied by scanning electron microscopy(SEM).

The background Adult-onset diabetes, also known as type 2 diabetes mellitus (T2DM), is a condition characterized by elevated blood sugar levels. It's marked by disruptions in carbohydrate, lipid, and protein metabolism due to irregular in insulin secretion, intervention, or both. Over the last decade, diabetes has reached epidemic levels in Iraq, mirroring global rises in the incidence of T2DM.

The amin drug ethyl-4-amino benzoate ( benzocaine ) was used for preparation two new azo compounds, with pyridoxine hydrochloride ( B6 ) (A6) and with ventolin ( salbutamol sulphate ) (A7). The two azo compounds were characterized by I.R., mass spectra and visible spectroscopic techniques. the electronic spectra of these azo compounds were investigated in terms of acid-base properties ,which includes establishing isobestic points, determination of protonation and ionization constants at various pH values ( 2-12 ). The effect of solvents of different polarities on the electronic spectra was the subject of the other research. The azo compound ( A7 ) has been also to determination of nitrite .

In this research, activated charcoal derived from cherry nuclei, which was activated with citric acid at a concentration of 0.6M, was used to adsorb estamperid from its aqueous solution, and the results showed the adsorption efficiency of R (76%), to study the kinetics of the adsorption of the activated charcoal of the pesticide. The adsorption process is subject to the rate of false second order, the thermodynamic processes were studied to find the value of the enthalpy in different degrees of temperature, and the adsorption process was automatic and endothermic, and the contact time for the adsorption of the pesticide on activated charcoal was also studied, and the best time was at half an hour and the best weight was (0.05gm). Six isotherm models were selected, and the results showed that the Frendelsh model applied to the adsorption process in this study supports the Tamkeen and Dubin model through the value of the constants. The results indicate that the ZPCpH value of the surface of carbonated coal derived from the cherry cores is within (10), meaning that the surface charge is positive within the value of this p=10. And the results showed an increase in the amount of adsorbed with the increase in the initial concentration, the kinetic adsorption results it is subject to a pseudo-second-order kinetic equation. The study included the choice of applying isothermate models (Langmuir, Freundlich, Temkin, Harkins-jura, Eiovich, and Doben).

Two amide resins, (bis-(2-hydroxy ethylene) terephthalamide) BHETA, and N1,N1,N4,N4 -tetra -(2-hydroxyethyl)-terephthalamide) THETA were prepared from reaction of waste water bottles (PET) with Monoethanolamine (MEA) and diethanolamine (DEA) respectively using microwave oven, (power less or equal to 600 w ) for 20 minutes. The products were characterized by FTIR spectroscopy then evaluated as corrosion Inhibitors for Carbon steel in 0.1 M HCl at different temperatures using Taffel plots and Electrochemical Impedance Spectroscopy (EIS) techniques. The obtained results showed that the Inhibition Efficiency (%E) increased up to 76% and 83% for BHETA and THETA respectively. The adsorption isotherm was investigated using Langmuir equation, and the obtained results confirmed the occurrence of physico adsorption that occurs between the Inhibitor and surface of the metal, and the thermodynamic functions were calculated : ads. ads. ) a ads. .
The coating properties of 25% w\w of each BHETA and THETA with commercial acrylic paint were evaluated using EIS technique and showed that the efficiency of coating increased up to 89% and 93.6% when adding BHETA and THETA respectively.

Tellurium with thiourea-derived bonds in the formula ( RNHCS2- or R2NCS2-) is a stable complex with yellow color and foul odor, characterized and analyzed by FT-IR, HNMR, and mass spectrometry. The percentage of elements included in the sample composition was known by EDX, EDS technique, and the surface topography was studied using a by Field Emission Scanning Electron Microscopy FSEM.

Cloud point extraction (CPE) method joined with Solvation method used for Separation and Determination Iron (III), the study shows up higher extraction efficiency for Iron (III) we got it at optimum conditions, 100 μg Fe3+ in 10 mL aqueous solution, (1×10-3 M) NaNO3, (1×10-4 M) Erythrosine, 0.5 ml Triton X-100 and heating of 85 ℃ for 15 minutes, as well as solvation species gave maximum absorbance at λmax = 543 nm, in addition to some effective experiments.

A new series of amides from different aromatic amines and2-phenyl thiazolidine-4-carboxylic acid which were prepared from the reaction of benzaldehyde with D-penicillamine under slightly conditions, thiazolidine have been synthesized in one step by cyclization of penicillamine with benzaldehydes in ethanol and water at room temperature . The amine group in the thiazolidine ring is protected by reaction with the acetic anhydride ,which was converted to the corresponding 3-aceylthiazolidine derivative . Reaction of N-aceyl-protected carboxylic acids with different amines using DDC/HOBt gave corresponding amides ,The general synthesis of 2-phenyl-thiazolidine-4-carboxylic acid amides is shown in Scheme 1. All products were characterized and identified by FT.I.R and 1H-NMR spectroscopy , and Finally a biological activity (antimicrobial) for the new prepared products were checked

Schiff bases are imine or azomethine-containing aldehydes or ketone-like compounds replacing the group carbonyl. They're widely utilized in industry, and they come in a variety range of biological processes. It has a wide Antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic characteristics are among the biological activities., and is commonly used in industry. Many Schiff bases complexes had high thermal and moisture stabilities, which were advantageous for their use as catalysts in high-temperature reactions. Because complexation generally increases activity, it's important to have a better understanding of the characteristics of both ligands. Medicinal chemists are now interested in developing Schiff bases and their metal complexes are novel chemotherapeutic Schiff bases. This is a review of gathers Schiff bases and complexes that have shown to be the most promising in various fields

In this paper, a new platinum (IV) complex was designed as a cancer treatment by and study by the Gaussian 09W program, Then the physical properties were calculated by the density functional theory DFT at B3LYP with basis (LanL2DZ) such as the total of the electronic energy, highest occupied molecular orbital (HOMO) lowest unoccupied molecular orbital (LUMO), Energy gap and other energy properties. ultraviolet - visible (UV) spectrum and the infrared (IR) spectrum, have been used, Thus, effectiveness of the complex and the interactions that can take place inside the human body, also have been studied, then comparing its link with the nitrogenous bases that make up the DNA, then exploring its connection with a small section of the DNA strand. The results showed that the proposed compound achieved chemical hardness similar to cisplatin binding with DNA under the same conditions and using the same method and the same basis rules. However, proposed complex's electrophilicity proposed complex's electrophilicity was less than cisplatin, which indicates its biological effectiveness towards cancer inhibition and the possibility of cancer cells not being resistant to it. The benefit of this study is to suggest new, more stable drugs that can be taken orally and achieve greater effectiveness in inhibiting the DNA of cancer cells.