Tikrit Journal of Pharmaceutical Sciences

The present study has been designated lo evaluate the antimicrobial activity of aqueous extract of Prosopis farcta pods. The antimicrobial activity of the extract against five fungal strains and four bacterial strains were tested by using Agar Well Diffusion method and minimal inhibitory concentration MIC values. The results showed that aqueous extract of P.farcta had antifungal and antibacterial effects against all the tested microorganisms, wherease Nystatin failed to show any effect against C.cladosporides. Therefore, these results suggest that the aqueous extract of P. farcta possess compounds with antimicrobial properties which can be used as antimicrobial agents in new drugs for therapy ofmicrobiaJ diseases in human

ln this research, Anthraquinone was prepared from the oxidation of anthracene (obtained from coal tar) by sodium perchlorate in presence of vanadium pentoxide as a catalyst in a good yield and high purity. Anthraquinone was formulated as a wettable powder (w.p.) to prepare a bird repellent pesticide> which leave no toxic residue in crop plants.

Data was collected from 60 cases in age groups from 40-60 years ( 30 female and 30 male ).The cases included in this study was collected randomly in Baiji hospital from June to October 2006 .
The data was obtained by using a questionnaire . It was found that the most common cases use Beta blockers as antihypertensive drugs , 12 cases use B-blocker plus Angiotensin converting enzyme
inhibitors and 5 cases use B-blocker with diuretics.There are 8 cases use Angiotensin converting enzyme inhibitor only and 7 cases use vasodilator drugs .Regarding the measurement of blood
pressure and heart rate , in 36 cases complaining from increase blood pressure above the normal level there is increase in heart rate in 30 cases ( heart rate more than 100 beat / minute ) , andin24
cases of normal blood pressure there is increase in heart rate in 5 cases only .The aim of this study is to investigate the prevalence of hypertension in age groups from 40-60 years in Baiji from June to
October with some investigations

Diazepam has become a commonly used drug for treatment of acute repetitive epileptic seizures and febrile convulsions in children. Considering the advantages of rectal administration of diazepam, the objective of this study was to formulate and evaluate rectal hydrogels containing diazepam as a drug substance in combination with suitable co - solvents and preservatives.Prepared HPMC (hydroxypropyl methylcellulose) hydrogels containing different concentrations of diazepam (2, 4 and 6 mg I ml) manifested good quality in respect to physicochemical parameters (pH value, drug content, ingredients content and viscosity), antimicrobial efficiency and microbiological quality. Under the proposed HPLC conditions, satisfactory separation of diazepam and the preservatives used was achieved. In vitro release studies have shown that the total amount ofdiazepam was released in a period of 3 hours. Prepared formulations were stable for four months at 26 C (ambient temperature characteristic of the second climate zone

This study was conducted at the North Gas Company in Kirkuk during the period from Nov. 2001 - July 2002. Four stations were chosen for sampling collections. The samples chosen from ; station (1) before treatment,and three stations from the treatment unit (production unit ;control unit; and general unit ). Four bacterial species (10 isolates for each) staphylococcus aureus;Enterococcus faecalis; Escherichia coli; and Pseudomonas aeruginosa were isolated.Results of the present study showed that minimum inhibitory concentration (MIC) of alcoholic extract for Gram positive bacteria isolates was (4 - 8 mg/ ml), while it was 4 - 16 mg/ ml for Gram negative bacteria

Gestational age has traditionally been used as strong indicator for the risk of neonatal morbidity and mofiality. Indeed, survival increases with increasing gestational age. Therefore a full-term neonate carries less morbidity and mortality in comparison with pretdrm neonate. Assessment of maturity requires the utilization of many physical and neurological criteria. Measurement of skin fold thickness is an easy maneuver. The aim of the present study is to assess whether the skin fold thickness is of benefit in the assessment of maturity. One hundred preterm and 10! full-term neonates, their skin fold thickness were measured by using the skin fold thickness caliper, the skin fold thickness of the preterm neonates (2.4 mm + 0.5) were found to be significantly lower than the skin fold thickness of the full-term neonates (4.2 mm+ 0.9) at aP value of less than 0.01. It is evident from this study that there was a strong positive correlation between the gestational age and the skin fold thickness, that is mean the skin fold thickness is higher with increasing gestational age. In conclusion; skin fold thickness can be considered as a palameter in the assessment of maturity of the newbom neonates.

This study was designed to evaluate the effectiveness of laser light radiation alone and laser-photosensitiser combination against Leishmania major amastigote in vitro. The result shows that laser-photosensitiser combination was more effective in killing than laser light alone. This effect may be photochemical due to absorption of laser light wavelength by exogenous photosensitiser which cause bond breaking leading to toxic effect on the amastigotes

The aim of this study was to evaluate and compare the in vitro and in vivo transdermal potential ofw/o microemulsion (M) and gel (G) bases for diclofenac sodium (DS). The effect of dimethylsulfoxide (DMSO) as a penetration enhancer was also examined when it was added to the Mformulation. To study the in vitro potential of these formulations, permeation studies wereperformed with Franz diffusion cells using excised dorsal rat skin. To investigate their in vivoperfoniranc e, a car-rageenan - induced rat paw edema model was used. The commercial formulationof DS (C) was used as a reference formulation. The results of the in vitro permeation studies andthe paw edema tests were analyzed by repeated - measures analysis of variance. The in vitropermeation studies found that M was superior to G and C and that adding DMSO to M increasedpermeation rate. The permeability coefficient (Kp) of DS from M and M + DMSO were higher(Kp :4.9 X 10 -3 +3.6 X l0 -4 cm lhand 5.3 X 10 -3 + l.2X 10 -3 cm / h, respectively) than the($p) of nS from C (Kp: 2.7 xl0-3 +7.3 X 10 -4 cm /h) and G (Kp:4.5 X i0 -3 x+.s X 10 -scm / h). In the paw edema test, M showed the best permeation and effectiveness, and M + DMSOhad nearly the same effect as M. The in vitro and in vivo studies showed that M could be a new,altemative dosage form for effective therapy.

Aqueous and alcoholic extract of Coriandrum sativum (Fruit) were evaluated against pathogenic bacteria. Results showed that the IMIC] of aqueous extract for these pathogenic bacteria (Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas auer and E. coli) ranged between (8192-16384) lglml while MIC of alcoholic extract for above pathogenic bacteria ranged between (4096-16334) ng/ml. There is no significant difference between the two extracts effectives