Iraqi National Journal Of Chemistry

The applied research on extract of active constituent from Iraqi myrtus communis
leaves using different polarity organic solvents ,then each extract was identify using
Fourier transmitting infrared FT-IR and high performance liquid chromatography
HPLC which comparing with merck index built in OPUS instrumental of FT
IR(atlas). Some standards were injected in HPLC , therefore we capable to know
many organic compounds were present in myrtus should be affected on manner of
plant .

Thio Bis-N, N substituted phthaldicarboximides were synthesized from the reaction
of phthalic anhydride with diamines (aliphatic and aromatic) in hot acetic acid. The
products were treated with phosphorous pentasulphide N-substituted Phthalimidines
were prepared by the reduction of N,N substituted phthaldicarboximide with zinc dust
and hydrochloric acid in ether.
While isoimides was synthesis through the reaction of phthalic anhydride with
diamines in the presence of trifloroacetic acid.

The study is concerned with the adsorption of terasil yellow (W-6GS) dye from
aqueous solution by using attapulgite clay , where the effects of initial concentration
of dye, pH and the equilibrium contact time, were investigated, also studies the effect
of acid, base and salt concentrations on the adsorption process. Isotherm of it’s
adsorption was measured.

In this work a new peptide-base polymer were synthesized by polycondensation of
cephalexinyl chloride and asparginyl chloride. This synthesized biopolymer is especially
interesting because its primary structure allows the specific cleavage through amide group ,
can also be used for site specific release of drug as we expected.
The physical properties of [C3] were measured. , FT-IR , 1H-NMR and UV. Spectroscopy
used to characterized the polymer [C3]. S % was calculated in water, and controlled release
was studied in different pH values at 370C.

The PM3 semi empirical MO method within the Gaussian 03 program was used
to study twelve newly synthesis compounds(1-12) along with the parent compound,1,
incorporating two heterocyclic 1,3,4-oxadiazole and 1,3,4-thiadiazole rings were studied
theoretically using . The geometric parameters, dipole moments, electron densities,
HOMO and LUMO energies and thermodynamics data Uo, Ho, So, Go, and Ao of these
compounds were reported. Finally, the intra molecular hydrogen bonding interaction
between oxygen and hydrogen atoms within the same compound was discussed .It was
shown that the compound with the NO2 substituent has the stronger intra hydrogen
bonding interaction.

The reactivity of the CNT-doped Y5Si3 compared to Y5Si3 phase system has been
investigated. Both alloys have been prepared by arc melting and their reactivity with
hydrogen has been studied. Single–phase CNT-doped Y5Si3 can only be made by melting
preformed Y5Si3 with the CNT. An activation process has been developed to induce
reaction of the doped alloy with hydrogen. It involves cycling in H2 gas pressures above
1.2 atm at temperature higher than 435oC depending on the CNT content. Conditioned
samples, will repeatedly (above 50 cycles) cycles 2.5 H (fu)-1 between room temperature
and 500oC with 0.9 and 1.2 H (fu)-1 being desorbed and absorbed with fast kinetic within
a very small temperature range. This behavior is believed to arise from the polymorphic
change between an α-form of the D88 structure and a supercell β-form. An attempt to
quantify the enhanced stability, compared to Y5Si3, is made by measuring reaction
enthalpies using Van’t Hoff isopleths.

In this search polyacrylic acid (PAA) hydrogels were synthesized by radical
polymerization in solution with N,N'-Methylene bis acryl amide (MBA), as
crosslinking agents and potassium persulfate (KPS), sodium metabisulfite (SMBS) as
type of mixed redox initiators, poly acrylic acid hydrogel structures were prepared by
using N,N'-Methylene bis acryl amide (MBA) as crosslinking agent (0.05, 0.1, 0.15,
0.2, 0.25 )g. at temperature 700C for 4 hr. The swelling ratio (Rs) was measured for
all the hydrogel structures, in three different media (pH=2), (pH=4) and (pH=7.2), and
three different temperatures (37, 45, 50 )0C as function of time. Theophylline was
loaded into polymeric matrix during in situ polymerization, The concentration of
theophylline released was measured on UV-Vis spectrophotometer. The drug release
studies from the theophylline loaded hydrogel was studied in three different media
(pH=2 ,4 and 7.2),and three different temperature (37, 45 and 50) 0C as function of
time. The results showed that the samples involving the highest release of
theophylline were arranged as follows :
PAA-MBA0.05 > PAA- MBA0.1 > PAA- MBA0.15 >PAA- MBA0.2>
PAA- MBA0.25

The study aims to determine the dissociation constant of 2-(2-hydroxyphenyl)
4,5-diphenylimidazole (HPI) ligand, and also to study the complexes formation, in
mixed (30 % H2O / 70 % dioxane), between the ligand and Cu (II), Ni (II), Co (II) and
Zn (II). Complex formation was traced and followed through measuring the stability
constants of the formed complexes.
Potentiometric technique was used, to follow the change in concentration of
one constituent in the reaction (titration) vessel during the coordination in solution.
The titration vessel contains: ligand, diluted strong acid and electrolyte salt to
maintain constant ionic strength of 0.1 mol.dm-3 KCl; a solution of divalent metal
added in case of the determination of complex stability constants. In this investigation
a hydrogen concentration was followed through measuring the pH of the solution at
various stages where basicity of the solution alters via adding alkali.
Coordination and measurements were taken place at 35 °C, and the
dissociation constant of the ligand with the stability constant of all the species formed
in the solution were calculated by means of the HYPERAUADE 2008 computer
program.

Azo derivative ligand[H3L] have been synthesized by the reaction of diazonium salt of
p-amino benzoic acid with orcinol in(1:1)mole ratio. The bidente ligand was reacted with
the metal ions MnII,FeIIandCrIIIin(2:1)mole ratio via reflux in ethanol using Et3N as a base
to give complexes of the general formula:[ M(H2L)2(H2O)x]Cly The synthesized
compounds were characterized by spectroscopic methods[ I.R , UV-Vis, A.A and
H1NMR]along with melting point, chloride content and conductivity measurements. The
complexes were screend for their in vitro antibacterial activity against one strain of
staphylococcus as Gram(+) positive and one strain of pseudomonas as Gram(-) Negative,
using the agar diffusion technique.

A novel drug polymer as a peptid-biopolymer was prepared from
histidineacidchloride with amoxillinacidchloride, the condensed polymer was
prepared with molar ratio 1:1, this biocompatible, biodegradable, reabsorb able
condensed polymers with controlled lifetimes, which can be used as drug carrier
polymer. The physical properties were measured and the intrinsic viscosity was
measured using Ostwald viscometer, The controlled release rates were studied in
different pH values at 37 0C . The condensed polymer was characterized by UV-vis.
FTIR and 1H-NMR spectroscopy, This biomaterial polymer can be used as non-toxic
substance. When it undergo hydrolytic degradation.

Co(II) , Ni(II), Cu(II) Zn(II) and Cd(II) metal complexes of new imidazol
dithiocarbamate of type [M(imid.dtc)2] and mixed ligands complexes of the type
[M(imid.dtc)2.phen] (phen=1,10-phenanthroline) have been synthesized and characterized by
elemental analysis (atomic absorption) infrared , electronic spectra , molar conductivity
measurements and magnetic measurements . It has been found that the imidazol
dithiocarbamate behaves as a monodentate ligand in all complexes . The suggest geometry of
the four coordinate complexes , appear to be square planer , while octahedral are expected for
mixed ligunds.

The present work study the adsorption and photolysis of chlorobenzaldehyde
in solution on the surfaces of Bentonite , Kaolin and Attapulgite.
UV- visible spectrophotometer technique ,pH and conductivity have been used to follow
the results,which showed a higher adsorption on kaolin surface than bentonite and
Attapulgite.
Rate of degradation reaction is 10.5 , 2.55 and2.1( mol/l.min-1 ) on kaolin,Bentonite and
Attapulgite respectively.
While the value of conductivity and pH were increased through adsorption process
when bentonite surface used.
Phtolysis processes for chlorobenzaldehyde showed higher rate of reaction in the
absence of any and equal to 4.65 ( mol/l.min-1) .A kinetic study was carried out for the
degradation of chlorobenzaldehyde different kind of clay .
The results showed first order reaction and a relatively high rate of reaction kaolin 4.5,
4.5 and 3.45 ( mol/l.min-1) on kaolin,Bentonite and Attapulgite respectively and a short
half life time ( 23.1,23.1 and 30.13 )min for the same surfaces .

The fatty acid composition of the seed oil of Gundelia L. which is grown in
Kurdistan Region-Iraq was determind. The percentage of seed oil was found to be
31.5%.
It has been found that the seed oil contain myristic, palmitic, palmitolic,
heptadecanoic, stearic, oleic, linoleic, and linolenic. Seed's oil contain high level of
oleic and linoleic acids, about 20-40%.