Tikrit Journal of Pharmaceutical Sciences

This study investigated the effects of Green tea aqueous extract and Vitamin I effect on the fertility of men, and the antioxidant and unti-infenile activity for comparison. The study included examination of (281) samples of seminal fluid of men thar were suffering from infertility caused by gonorrhea n :(144) , Varicose n: (47) , seminal vessels narrow 0: (31) , different inflammations n: (59) samples . and (60) samples from normal individuals (subjects) as a control, for the period from March(2008) 10 April(2009) in Tikrit city and its surrounding. The results appeared that adminstratio of green tea extract alone or with Vit. E in an infertile men (Gonorrhea infections, Varicocele |, Seminal vessels narrow and different sexual inflammations) lead to significant increase (p<0.03) in total numbers , the average of movement and normal forms of sperm. The treatment with Vit. k alone lead to increase in numbers and normal forms of spermatozoa , however , no significant variations were of served in the average of movement. The results indicated that using green tes agueous exirct , VitE or both logether were effective to inducing significant increase in the concentrations of testosterone hormone. In noma) cases the results showed no significant variation in total numbers of sperms after with preen tea extract or ViLE adminstration. whereas acminstration both together showed a significant increase , also an increase in the average of movement and normal forms when patints treated with green tea extract alone or green extract incombination with VitFE bu no significant variations were observed when treated with Vit.E alone The results emphasized that using Vit. E or green tea extract or both together were effective in inducing a significant increase in the concentration of lestosicrone hormone The causes of the green lea extract effectivness relate 10 its consistence of antioxidants which reduced the free mdicals in the infertile men and caused an improvement of their fertility.

The study aims to evaluate the effect of some natural products (nigella sativa. sesame, flax amd ginger oil) (Emad factory/mosul/Iraq) in relation to nystutin suspension on color of GC-Soft Liner Fifly Sample were prepared frum-GC-extra soft lining material, they were (10*10%2mm). Half of the samples for each group were immersed for 8hr in these oils after they had been infected with Candida albicans and incubated [ur 48hr, the other half of the samples immersed for Bhr daily fur one month. This study compared antifungal efficiency before and after immersion in distilled water (Negative Control), nystatin suspension (100000 LU/ml as a positive control), nigella sativa, sesame, flax and ginger oil. Color of samples tested by Vita — Easy Shade system, the statistical tests used were analysis of variance, Durinet T-test. The resulls demonstrated that there were significant differences between all tested oils znd DW in refution to antifungal action, and no significant differences between all tested oils and D.W iu relation 0 color of GC-solt Lining maternal al (P=0.05). All the tested natural oils were effective antifungal agents and would be accepted and safe in relation to the color of soft hnet.

Cervical — Lymphadenopathy is common problem , both in children and adults. Aim of study . to determine the most professional — dinguosis ul cervical — Lymphadenopathy according to patient age . over period Lasting from Jan - 2007 to Nov . 2009 , prospective study of ( 83) patients from ( both sexes ), ( male : 51 ){ Female : 32) with cervical — Lymphadenopathy were taken and divided into two age groups ( pediatric age group < Sy ) and ( Adult age group 16-72 y) . Diagnosis of cervical —

Lymphadenopathy depend on clinical — examination , radiological — examination , FNA(Fine Needle Aspiration) , and in some cases excisional biopsy was taken. Result :

this study showed that inflammatory and infectious diseases had the highest incidence in pediatric age group ( 65.7%) of total pediatric cases , followed by primary malignant cervical — Lymphadcnopathy ( 25.7% ) , the lowest was the secondary imelasteses (8.6% )- while in adult age group secondary cervical Lymphedenopathy (metastases) was the commonest ( 41.71 ) Followed by infectious and inflammatory Lesion ( 37.51) , the Lowest was the primary ervival — Lymphadenopathy (20.8%) Conclusion : In this smudy infectious and inflammatory cervical — lymphadenopathy was the commonest in pediatric age group , while secondary cervical lymphadenopathy —( metasteses) was the commonest in adult age group .

Yield of TURP-TURBT (lransurethral resection of prostate transurethmal resection of bladder tumor) in Mosul has not been studied before. Prostatic & bladder cancers are increasing in this specific locality, to know their frequency and grades this study was donc. Four hundred and ninety TURP-TURBT chips were received, examined grossly, processed routinely, and then analyzed microscopically. The study was performed in Alzahrawi hospital - histopathology laboratories of Mosul city in Iraq between January 2006 and through December 2007. There were 320 (65.3%) were taken hy TURP and 170 (34.7%): were taken by TURBT (142 male and 28 female). Benign prostatic hyperplasia was the predominant TURP finding (282; 88.1% cases), while prostatic carcinoma was found in 38 (11.9%) cases. Most of the prostale cancer cases were received as high grades (Gleason's grade 4 and 5). Transitional cell carcinoma was the chief TURBT finding (149; 87.6'%). prostatic carcinoma and transitional cell carcinoma are common in this locality. Most cases of prostate carcinoma were diagnosed as high grades.

The current study was designed to verify the implication of pregnancy in the induction of serum lipid and lipoprotein changes in pregnant women . To achicve this aim ,50 pregnants and 50 age matched healthy non pregnant women {control group) were enrolled. Serum Iron, Hb, cholesterol . TIBC triglyceride, HDL — cholesterol . LDL- cholesterol ,VLDL- triglyceride concentration were measured in all subjects. Significant (P<0.0) increases were found in the levels of serum TIBC, cholesterol, triglyceride. LDL and VLDL in the pregnant women of third trimesters when compared with those of the control group. HDL levels were found to be significantly (P<0.0) elevated in pergnants of the third trimesters with those of the control group. Significant (P<0.0) decreases were found in the levels of serum iron and Hb in the pregnant women when compared with control group.

Otalgia is the sensation of pain in the car, while referred otalgia Is pam felt in the ear but originating from non-otological source Lar pain is a diagnostic problem when examination of the ear shows no pathology. A prospective study was conducted in EN.T - private clinics in Kirkuk city from October 2007 to December 2008. Age , sex and causes of referred ofalgia were noted, During the study period 210 patients were evaluated , out of 210 patients 122 male "58%" and 88 females "42%", Tonsillitis,pharyngitis and post tonsillectomy were the commonest cause"S1 4%" Three patients had malignancy of upper aerodigestive tract and referred otalgia was one of its main symptoms. Referred ear pain is more commonly caused by tonsillitis , pharyngitis

but it may be first symplom of head and neck malignancy,

Abstract Cutaneous loishrnaniasts (CL) is a parasitic disease characterized by single or multiple lesions,. Sc ontlay bacterial infection is one of the complications of the Jiscase that Can increase the titute destruction and the resultant sear. To determine effectively the u3cidence of real tamaindary bacterial infection in the dry type, of cutaneous leishmaniasis ,we designed the current study. This was a crusts-sectional study performed in the outpatient clinic of dermatology and vencriology nt Unit Teaching Hospital. A total of 37 patients with etinica3 diagnosis of Cutaneous leishmaniasis (dry type) were, carolled in this study. Samples were taken from all patients. The skin areas surrounding the lesions were thoroughly cleaned using cotton wool moistened with alcoholic iodine. After appropriate cleaning, the samples were collected aseptically by scraping of sterile swabs of the lesions All the samples were transferred uo Mac Cunkeys agar and blood agar_ After 24 hours incubation (aerobically& en aerobically) at 37 tIC, the species atilt bacteria were determined. Then site samples were transferred to Mueller-Hinton agar or nutrient agar for sensitivity test. After 24 hours incubation at 37 °C, the diameters of the inhibition zones were measured to determined the sensitivity Among the 37 patients with Cutaneous leislununiasis the results of the culture were positive in 12 patients (32.4%). 11 of them (91.6%) have more than one lesion and 9 patients (75%) of them were less than 5 years old. and 3 patients (25%) were more than 5 years old_ Bacteria isolated from the lesions were Staph. aureus in II patients (91.6%)( and all were sensitive to Rifampicin) and E.Coli in one patient (LI%) which was sensitive to Amikacin & Norlioxacini The incidence of secondary bacterial infection with a dry type of Cl., was (32.4%), (91.6%) of them had multiple lesions, and (75%) were less than 5 years old, The most common bacterial isolate was Staphylouocus ttureus

bs tract Isonicotinic acid, o-hydroxy benzoic acid, p-chlorobenzoic acid p-nitro benmteacid and 0-acetyl benzoic acid, have ben csterificated with absolute ethanol wing Fisher method to prepare compounds [I-5J. -Most compounds %vac converted to acid hydra idef; [6-10] by the reaction with hydrazine hydrate. The avid hydrazides were allowed to react with carbon disulfide (CS2) in the presence of potassium hydroxide and ethanol to pmduce 2-substituted 1, 3, 4- oxadia7nic -5-thiol 111-15]. Thio ether derivatives as two groups (16-20) and (21-25) respectively have been prepared by the reaction between compounds 111-15] and alkyl or aryl halide, (p-bromn bcnzyl bromide and 2.4- dinitrochlurubenzene) respectively. The prepared compounds Were identified by FI_LR melting point and I WAS used to support the structure of the compounds 2-(4-chloropheny1)-5-(2,4- dini trophcny I thio)- 1 ,4-oxad iazo le and 2-(2,4-d initropheny I dtio)-3-(4-nitrophenyl)- I ,3,4- oxadiszole which can be uazd as anti bactaial and anti fungus agents