Abstract
The major goal of this research was to determine how well NiO nanoparticles (NPs) inhibited the growth of harmful bacteria that were separated from biofilm layers that had developed inside of medical equipment used on a regular basis in hospitals and dental offices. Chia seed extract was previously used in the preparation and physical characterization of NiO nanoparticles. Thirty isolates of Pseudomonas aeruginosa (n=16) and Staphylococcus aureus (n=14) were found in separate swab samples taken from dental office bottles, syringe tubes, spittoons, ventilation machine tubes, and emergency room bottles. Using conventional bacteriological techniques, moist swab samples were inoculated and identified on culture medium, and subsequently antibiotic susceptibility was assessed in accordance with NCCLs. Using two different techniques—well diffusion and microdilution, respectively—the antibacterial activity of NiO nanoparticles against contaminated bacteria was assessed both qualitatively and quantitatively.
Keywords
Biofilm
MDR
nanomaterial
NiO NPs
P. aeruginosa
S. aureus
Keywords
المواد النااووياة، الاغشية الحيوية