Abstract
Cytomegalovirus infection considered one of the most important viruses that causes hearing loss, mental retardation, and cerebral palsy are all common side effects of infection person. Young children and personal connections are the most common causes of infection during pregnancy. As a result, it's a significant public-health issue. Congenital CMV (cCMV), the most public non-genetic cause of sensori-neural hearing loss, is linked to maternal infection. CMV can also induce cerebral palsy and cognitive impairment. CMV is spread through contact with body fluids from a viral carrier. After primary infection, Viruses are transmitted at higher level than other time of infection, and it increases with gestational age. When infection develops before 20 weeks, however, severe fetal consequences are more likely. Past infection does not provide the mother immunity or provide protection to the fetus. On ultrasonography, CMV can cause cerebral or extracerebral abnormalities, as well as fetal development limitation and loss. Seroconversion in pregnancy (de novo appearance of virus-specific immunoglobulin G (IgG) in the serum of previously seronegative pregnant women) or the detection of specific immunoglobulin M (IgM) and IgG antibodies in association with low IgG avidity should be used to diagnose primary maternal CMV in pregnancy. The effective method for preventing viral infection is to provide pregnant women with hygiene advice and education. Vaccines, antiviral medicines, and immunoglobulin have all had their roles expanded throughout time.