Abstract
New cobalt (II) complexes with mixed ligands including [(2- oxime-4-hydrazone) pentane (L1H)
and 2-chlorobenzaldehyde thiosemicarbazone(T1H) ,or 3,4-dimethoxy acetophenone
thiosemicarbazone (T2H); glycine (GH) or metformin (mf)] have been prepared in both pH (6.5-7)
and (9.5-10) using classical and microwave techniques. The resulting complexes have been
characterized using physio- chemical and spectral techniques. The study suggested that the
complexes have the generalformulate: [Co(L1H)(TH)(BH)](CH3COO) 2 at pH (6.5-7) and
[Co(L1)(TH)(G)]or[Co(L1)(T)(mf)) at (9.5- 10), respectively {where TH= T1H or T2H; T=
deprotonated T1H or T2H; L1H=L1=deprotenated; BH= GH or mf; G= deprotonated GH].
Hexacoordinated mononuclear complexes having distorted octahedral geometries have been
investigated. No laser effects have been observed on solid ligands and complexes indicating that the
compounds are stable and not affected by He-Ne laser (wave length are = 600- 700 nm). The
biologicall activity of the ligands and complexes have been evaluated by agar plate diffusion
technique against Echerichia coli, Klipsila pnnemoia, Staphylococcus aureus and Pseudomonas
aeruginosa. Some compounds have been found to have antibacterial activity.
and 2-chlorobenzaldehyde thiosemicarbazone(T1H) ,or 3,4-dimethoxy acetophenone
thiosemicarbazone (T2H); glycine (GH) or metformin (mf)] have been prepared in both pH (6.5-7)
and (9.5-10) using classical and microwave techniques. The resulting complexes have been
characterized using physio- chemical and spectral techniques. The study suggested that the
complexes have the generalformulate: [Co(L1H)(TH)(BH)](CH3COO) 2 at pH (6.5-7) and
[Co(L1)(TH)(G)]or[Co(L1)(T)(mf)) at (9.5- 10), respectively {where TH= T1H or T2H; T=
deprotonated T1H or T2H; L1H=L1=deprotenated; BH= GH or mf; G= deprotonated GH].
Hexacoordinated mononuclear complexes having distorted octahedral geometries have been
investigated. No laser effects have been observed on solid ligands and complexes indicating that the
compounds are stable and not affected by He-Ne laser (wave length are = 600- 700 nm). The
biologicall activity of the ligands and complexes have been evaluated by agar plate diffusion
technique against Echerichia coli, Klipsila pnnemoia, Staphylococcus aureus and Pseudomonas
aeruginosa. Some compounds have been found to have antibacterial activity.
Keywords
Cobalt (II) complexes
metformin glycine
Mixed ligands
thiosemicarbazone
Keywords
مزيج الليكندات، معقدات الكوبلت ) II)، ثايوسيميكاربازون ، ميتفورمين، كاليسين.