Abstract
A series of 1,3-diarylprop-2-en-1-one oximes (7-12) were synthesized via
reaction of 1,3-diarylprop-2-en-1-one (1-6) with NH2OH. HCl in dry pyridine. In
order to produce the required products (13-18) as anti-isomers, these products (7–
12) were then treated with acetic anhydride in dry pyridine. Different substitutes are
maintained, resulting in the separation of different products in different yields The
recently produced esters are thought to be useful as building blocks for the synthesis
of substituted pyridines and many other nitrogen-holding complexes, which are
elaborate structures in medicinal chemistry and present in a variety of
pharmaceutical medications. The synthesized products were characterized and their
structural details were clarified using 1H NMR spectroscopy of a representative one
sample ester and oxime, (FT-IR, UV) investigations, and melting point analysis.
Besides the elemental micro analysis (C, H, N) of the same samples, the suggested
mechanisms for these reactions were investigated according to these calculations.
reaction of 1,3-diarylprop-2-en-1-one (1-6) with NH2OH. HCl in dry pyridine. In
order to produce the required products (13-18) as anti-isomers, these products (7–
12) were then treated with acetic anhydride in dry pyridine. Different substitutes are
maintained, resulting in the separation of different products in different yields The
recently produced esters are thought to be useful as building blocks for the synthesis
of substituted pyridines and many other nitrogen-holding complexes, which are
elaborate structures in medicinal chemistry and present in a variety of
pharmaceutical medications. The synthesized products were characterized and their
structural details were clarified using 1H NMR spectroscopy of a representative one
sample ester and oxime, (FT-IR, UV) investigations, and melting point analysis.
Besides the elemental micro analysis (C, H, N) of the same samples, the suggested
mechanisms for these reactions were investigated according to these calculations.
Keywords
1
3-Diaryl-2- propen-1-one oxime
Chalcone oxime
Oxime acetate
Oxime O-ester
α
β-Unsaturated oxime