Abstract
This study investigates the sol-gel synthesis of aluminum oxide (Al₂O₃) and silicon oxide (SiO₂) nanoparticles, with a particular emphasis on mullite (3Al₂O₃•2SiO₂). The precursors used were TEOS (99.95%), Al(NO₃)₃•9H₂O (98.99%), and anhydrous citric acid (C₆H₈O₇, ≥99.5%) to produce a gel without any further purification. The resulting amorphous gel underwent dehydration and was sintered for 2 hours at 80°C. then, the samples were calcined at 900 oC. The synthesis involved equal amounts of Si(OC₂H₅)₄ and Al(NO₃)₃•9H₂O. The produced nanoparticles\\\\' structural and morphological characteristics were characterized using FTIR, XRD, AFM, UV, and FE-SEM. XRD examination showed rhombohedral Al₂O₃, SiO₂, and mullite production, with an average crystallite size of 26 nm. Synthesized Al₂O₃ and SiO₂ nanoparticles were tested for antibacterial abilities against E. coli and S. aureus. The inhibition zones for S. aureus and E. coli were 26.03 and 20.83 mm, respectively, indicating antibacterial effectiveness. At 100 mg/mL nanoparticles, 70% inhibition was reported. This research found that sol–gel-produced mullite and oxide nanoparticles are efficient broad-spectrum antibacterial agents.
Keywords
Al2O3
Antibacterial Activity
E. Coli
Mullite
S. aureus
SiO2
Sol–gel process